LYMPHOID NEOPLASIA Deficiency of SATB1 expression in Sézary cells causes apoptosis resistance by regulating FasL/CD95L transcription
نویسندگان
چکیده
1Department of Dermatology and Venerology, Peking University First Hospital, Beijing, China; 2Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC; 3Chieng Genomics Centre, Molecular Medicine Laboratory, Vancouver Coastal Health Research Institute, Vancouver, BC; 4Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC; 5Institute of Dermatology, Anhui Medical University, Hefei, China; and 6Department of Medical Genetics, University of British Columbia, Vancouver, BC
منابع مشابه
Deficiency of SATB1 expression in Sezary cells causes apoptosis resistance by regulating FasL/CD95L transcription.
Sézary syndrome (SS) is an aggressive subtype of cutaneous T-cell lymphoma that is characterized by circulating leukemic Sézary cells. The accumulation of these malignant cells has been shown to be the result of the resistance to apoptosis, in particular, activation-induced cell death. However, the mechanism of apoptosis resistance remains unknown. By characterizing the gene transcription profi...
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Department of Dermatology, Zürich University Hospital, Zürich, Switzerland; Louis-Jeantet Skin Cancer Laboratory, Department of Pathology and Immunology, University Medical Center, Geneva, Switzerland; Department of Dermatology, University Hospital, Geneva, Switzerland; Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia; Topotarget Switzerland, Lausanne, Swit...
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